Molecular pathophysiology of congenital long QT syndrome

MS Bohnen, G Peng, SH Robey… - Physiological …, 2017 - journals.physiology.org
… for LQT1 patients and predicting … the risk stratification for cardiac events in this set of patients
(Figure 9, A–C). While patients with K + channel-associated LQT are generally at higher risk

The genetic basis of long QT and short QT syndromes: a mutation update

PL Hedley, P Jørgensen, S Schlamowitz… - Human …, 2009 - Wiley Online Library
… of the QT interval as measured on electrocardiogram (ECG). Prolonged QT interval and a …
shortened QT interval with tall peaked T-waves and a propensity for atrial fibrillation. Both …

[HTML][HTML] Towards Mutation-Specific Precision Medicine in Atypical Clinical Phenotypes of Inherited Arrhythmia Syndromes

T Nakajima, S Tamura, M Kurabayashi… - International Journal of …, 2021 - mdpi.com
… strategies, especially in long QT syndrome. It is now known … mechanisms of diLQTS, predict
the arrhythmogenic risk of drugs, … -specific iPSC-CMs may facilitate patient risk stratification. …

Investigation and management of sudden unexpected death in the young in Canada

LJ Dewar - 2016 - summit.sfu.ca
… These disorders include long QT syndrome, short QT syndrome, catecholaminergic polymorphic
ventricular … The QT interval is affected by the heart rate, age and sex of the patient. A …

[PDF][PDF] Ionic, cellular and molecular mechanisms underlying the QT prolongation and arrhythmias in diabetic cardiocomplications

Y Zhang - 2006 - papyrus.bib.umontreal.ca
K channelopathy serves as the ionic basis for diabetic QT … have been considered as a predictor
of mortality in diabetic … This report described the first finding of ‘type 4 long QT syndrome’ …

[BOOK][B] Pathophysiology and pharmacology of short QT syndrome gene mutations in the human atria: Insights from multi-scale computational modelling

DG Whittaker - 2018 - search.proquest.com
… cava K+ Potassium ion LA Left atrium LAA Left atrial appendage LQTS Long QT syndrome
… Sodium channels then inactivate before reaching the predicted equilibrium potential for Na+…

[HTML][HTML] Calcium handling defects and cardiac arrhythmia syndromes

K Kistamás, R Veress, B Horváth, T Bányász… - Frontiers in …, 2020 - frontiersin.org
… As in the case of the working myocardium, K + currents repolarize … LQTS is characterized
by a prolonged QT interval on the … effective risk stratification and clinical guidance for all of the …

[PDF][PDF] in Diabetic Cardiocomplications

Y Zhang - 2005 - collectionscanada.gc.ca
… to one fourth of diabetic patients have prolonged QT interval. … and has been considered as
a predictor of mortality in both type … K" channelopathy serves as the ionic basis for diabetic QT

[BOOK][B] Syncope: mechanisms and management

BP Grubb, B Olshansky - 2008 - books.google.com
predictor of death, although for specific conditions, such as dilated cardiomyopathy,
arrhythmogenic right ventricular cardiomyopathy, congenital long QT interval syndrome… of isk, and …

Genetic and clinical features of familial Meniere's disease in Northern Ostrobothnia and Kainuu

E Hietikko - 2013 - oulurepo.oulu.fi
potassium voltage-gated channel subfamily A member 1, … potassium voltage-gated channel
subfamily E member 1, Isk-… as the potassium channel component encoding gene potassium